effects of coenzyme q10 on hemoglobin a1c, serum urea and creatinine in alloxan-induced type 1 diabetic rats

coenzyme q 10 is a natural antioxidant and free radicals scavenger. in the present study, we examined effect of coenzyme q 10 on hemoglobin a 1c , serum urea and creatinine in alloxan-induced type 1 diabetic rats. thirty sprage-dawley male rats were divided into three groups randomly; group one as control, group two diabetic untreatment, and group three treatments with coenzyme q 10 (15 mg/kg i.p daily), respectively . diabetes was induced in the second and third groups by alloxan injection subcutaneously. after 8 weeks, animals were anaesthetized; blood samples were collected to measure the hemoglobin a 1c , serum glucose, urea and creatinine . coenzyme q 10 significantly decreased hemoglobin a 1c , serum glucose, urea and creatinine . coenzyme q 10 exerts beneficial effects on the hemoglobin a 1c and serum glucose in alloxan-induced type 1 diabetic rats.